Rare Immunology News

5 Facts you should know about

Autoimmune hepatitis

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1

Autoimmune hepatitis may present as completely asymptomatic

(12–35% of the cases), with signs of chronic liver disease, or acute or even fulminant hepatic failure.

2

Common initial symptoms include fatigue or muscle aches

or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain.

3

The disease may occur in any ethnic group and at any age,

but is most often diagnosed in patients between 40 and 50 years of age.

4

Anomalous presentation of MHC class II receptors on the surface of liver cells

causes a cell-mediated immune response against the body's own liver, resulting in autoimmune hepatitis.

5

Virtually all patients have increased circulating IgG levels.

Rare Immunology News